Trial Entry Criteria

Consult with a healthcare professional to see if you meet the entry criteria.

How do I qualify?

Inclusion Criteria:

  • Male and female subjects between 18 and 65 years of age, inclusive
  • Diagnosis of Pompe disease

Enzyme Replacement Therapy (ERT)-experienced subjects (ambulatory) have:

  • Received ERT with alglucosidase alfa for the previous 2-6 years
  • Must be able to walk 200-500 meters on the 6-Minute Walk Test (6MWT )
  • Upright Forced Vital Capacity (FVC) 30% to 80% of predicted normal value

ERT-experienced subjects (non-ambulatory):

  • Received ERT with alglucosidase alfa for ≥2 years
  • Wheel chair bound

ERT-Naïve subjects (ambulatory):

  • Must be able to walk 200-500 meters on the 6MWT
  • Upright FVC must be 30% to 80% of predicted normal value
  • Subject has never received alglucosidase alfa